8-Methoxypsoralen

CAS: 298-81-7

Ref. 3D-FM08242

Product Information

• Name: 8-Methoxypsoralen
• Synonyms: MethoxsalenXanthotoxin8-MOP9-methoxy-7H-Furo[3,2-g][1]benzopyran-7-one, 5-Benzofuranacrylic acid, 6-hydroxy-7-methoxy-, δ-lactone, 5-Demethoxyisoimpinellin, 6-Hydroxy-7-Methoxy-5-Benzofuranacrylic Acid Delta-Lactone, 6-Hydroxy-7-methoxy-5-benzofuranacrylic acid-γ-lactone, 7-Furocoumarin, 7H-Furo[3,2-g][1]benzopyran-7-one, 9-methoxy-, 8-Methoxy, 8-Methoxy-2',3',6,7-Furocoumarin, 8-Methoxy-4',5':6,7-furocoumarin, 8-Methoxy-6,7-furanocoumarin, 8-Methoxy[furano-3',2':6,7-coumarin], 8-Methoxy[furano-3′,2′:6,7-coumarin], 8-Methoxyfuranocoumarin, 8-Methoxypsoralene, 8-Mop, 8-Mp, 9-Methoxy-7H-furo[3,2-g] [1]benzopyran-7-one, 9-Methoxyfuro[3,2-G]Chromen-7-One, 9-Methoxyfuro[3,2-G]Chromene-7-One, 9-Methoxyfuro[3,2-g]chromen-7-on, 9-Methoxypsoralen, 9-Metoxifuro[3,2-G]Cromen-7-Ona, 9-methoxy-7H-furo(3,2-g)benzopyran-7-one, 9-methoxy-7H-furo[3,2-g]chromen-7-one, Ammodin, Ammoidin, Deltapsoralen, Geroxalen, MOP, Meladinin, Meladinine, Meladoxen, Meloxine, Methoxa-Dome, Methoxalen, Methoxsalene, New-Meladinin, Nsc 45923, Oxsoralen, Oxsoralen Lotion, Oxsoralen Ultra, Oxypsoralen, Proralone-Mop, Psoralen-Mop, Psoralon-MOP, Puvalen, Puvamet, Uvadex, Vitpso, Xanthotoxin, Xanthotoxine, Xanthoxin, Zanthotoxin

Description

8-Methoxypsoralen (8-MOP) is a chemical that is used in the treatment of skin cancer. It inhibits the action of DNA polymerase and topoisomerase II, which are enzymes required for DNA replication. 8-MOP has been shown to be effective at inhibiting the growth of tumor cells in vitro, but it also exhibits minimal toxicity in vivo, suggesting that it may be a good candidate for use as an anti-cancer agent. 8-MOP can inhibit the growth of squamous cell carcinoma cells and T-cell lymphomas by blocking DNA synthesis. 8-MOP also inhibits the proliferation of HL60 cells by blocking RNA synthesis and protein synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 216.19 g/mol
• Formula: C₁₂H₈O₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
• InChI key: InChIKey=QXKHYNVANLEOEG-UHFFFAOYSA-N
• SMILES: COc1c2occc2cc2ccc(=O)oc12