Methyl 2,6-difluoronicotinate

CAS: 117671-02-0

Ref. 3D-FM100742

Product Information

• Name: Methyl 2,6-difluoronicotinate

Description

Methyl 2,6-difluoronicotinate is a regioselective dopamine receptor antagonist. It is a carboxylic acid that reacts with esters to form a nucleophilic anion. Methyl 2,6-difluoronicotinate has been shown to be an effective dopamine D2 receptor antagonist in rats and monkeys. This drug was also able to inhibit the binding of dopamine to the D3 receptor in rat striatal synaptosomes. The regioselectivity of this drug allows for preferential binding at the D2 receptor over other sites such as the D1 or D4 receptors.

• Brand: Biosynth

Chemical properties

• Molecular weight: 173.12 g/mol
• Formula: C₇H₅F₂NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C7H5F2NO2/c1-12-7(11)4-2-3-5(8)10-6(4)9/h2-3H,1H3
• InChI key: InChIKey=FTFGRVXYRDOUJN-UHFFFAOYSA-N
• SMILES: COC(=O)c1ccc(F)nc1F