3-Methylindole

CAS: 83-34-1

Ref. 3D-FM10897

Product Information

• Name: 3-Methylindole
• Synonyms: 1H-Indole, 3-methyl-, 3-Methyindole, 3-Methyl indole, 3-Methyl-1H-indole, 3-Methyl-4,5-benzopyrrole, 3-Methylindol, 3-Metilindol, Beta-Methylindole, Fema 3019, Indole(1H), 3-Methyl-, Indole, 3-methyl-, Indole, 3-methyl-(skatole), Nsc 122024, Scatole, Skatol, Skatole, β-Methylindole

Description

3-Methylindole is a chemical compound that is found in wastewater. It is an inhibitor of cytochrome P450 and has been used for the treatment of indole, which is a chemical compound that is produced by gut bacteria. 3-Methylindole inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 3-Methylindole also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

• Brand: Biosynth

Chemical properties

• Molecular weight: 131.17 g/mol
• Formula: C₉H₉N
• Purity: Min. 97.5%
• Color/Form: White Powder
• InChI: InChI=1S/C9H9N/c1-7-6-10-9-5-3-2-4-8(7)9/h2-6,10H,1H3
• InChI key: InChIKey=ZFRKQXVRDFCRJG-UHFFFAOYSA-N
• SMILES: Cc1c[nH]c2ccccc12