MY 5445

CAS: 78351-75-4

Ref. 3D-FM137621

Product Information

• Name: MY 5445
• Synonyms: (3-Chloro-phenyl)-(4-phenyl-phthalazin-1-yl)-amine, 1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl-, My-5445, N-(3-Chlorophenyl)-4-phenyl-1-phthalazinamine, N-(3-chlorophenyl)-4-phenylphthalazin-1-amine

Description

MY 5445 is a nonsteroidal anti-inflammatory drug (NSAID) that is selective for COX-2. It has been shown to be a specific treatment for chronic and acute inflammatory diseases, such as arthritis, ankylosing spondylitis and osteoarthritis. Clinical studies have shown that MY 5445 reduces the levels of pro-inflammatory cytokines in the blood and has an anti-nociceptive effect by inhibiting the release of prostaglandin E2. This drug also inhibits cell growth, which may be due to its ability to inhibit cyclase and cyclic nucleotide phosphodiesterases.

• Brand: Biosynth

Chemical properties

• Molecular weight: 331.8 g/mol
• Formula: C₂₀H₁₄ClN₃
• Purity: Min. 95%
• InChI: InChI=1S/C20H14ClN3/c21-15-9-6-10-16(13-15)22-20-18-12-5-4-11-17(18)19(23-24-20)14-7-2-1-3-8-14/h1-13H,(H,22,24)
• InChI key: InChIKey=CEHQLKSLMFIHBF-UHFFFAOYSA-N
• SMILES: Clc1cccc(Nc2nnc(-c3ccccc3)c3ccccc23)c1