5,6-Methylenedioxyindole

CAS: 267-48-1

Ref. 3D-FM137841

Product Information

• Name: 5,6-Methylenedioxyindole
• Synonyms: 5H-[1,3]Dioxolo[4,5-f]indole, 1H-Indole, 5,6-[methylenebis(oxy)]-, 2H,5H-[1,3]Dioxolo[4,5-f]indole, 5,6-(Methylenedioxy)indole, 5,6-Methylenedioxy-1H-indole, 5H-1,3-Dioxolo(4,5-f)indole, 8aH-[1,3]dioxolo[4,5-f]indole, Brn 0132678, Nsc 92516

Description

5,6-Methylenedioxyindole (MDI) is a compound that is often used in the synthesis of other bioactive molecules. It has been shown to bind to the pyridinium moiety of receptor sites and form a stable complex, which can then be displaced by an agonist or antagonist. The binding experiments were performed using radioactive MDI and zoxazolamine as the ligand. Radiolabelled MDI was synthesized from 5-methyl-2-pyridinone with the use of a linker, methylenetriphenylphosphorane (MTPP). The molecular electrostatic potentials of the two compounds were calculated in order to investigate the possible binding interactions between them. Ellipticines are also synthesised using MDI as a precursor molecule, which is alkylated with dimethyl sulfate and then reacted with phenylhydrazine. This reaction produces a mixture containing both ellipticines and

• Brand: Biosynth

Chemical properties

• Molecular weight: 161.16 g/mol
• Formula: C₉H₇NO₂
• Purity: Min. 95%
• InChI: InChI=1S/C9H7NO2/c1-2-10-7-4-9-8(3-6(1)7)11-5-12-9/h1-4,10H,5H2
• InChI key: InChIKey=HXCHORPNRVSDCD-UHFFFAOYSA-N
• SMILES: c1cc2cc3c(cc2[nH]1)OCO3