4-Methoxybenzene-1,3-diamine sulfate

CAS: 39156-41-7

Ref. 3D-FM140848

Product Information

• Name: 4-Methoxybenzene-1,3-diamine sulfate

Description

4-Methoxybenzene-1,3-diamine sulfate (4MBD) is a chemical substance that inhibits the activity of cytochrome P450 enzymes. It has been shown to inhibit the activity of rat liver microsomal p-450 enzymes, and is used in studies on the effects of chemicals on protein synthesis. When 4MBD is administered to rats at dietary concentrations, it causes an increase in thyroid hormone levels and a decrease in renal function. The enzyme inhibition caused by 4MBD may be due to its ability to acylate amines, which are located near the active site of the enzyme. Linear regression analysis showed that there was a strong correlation between dietary concentrations and the inhibition of protein synthesis caused by 4MBD.

• Brand: Biosynth

Chemical properties

• Molecular weight: 236.25 g/mol
• Formula: C₇H₁₂N₂O₅S
• Purity: Min. 95%
• InChI: InChI=1S/C7H10N2O.H2O4S/c1-10-7-3-2-5(8)4-6(7)9;1-5(2,3)4/h2-4H,8-9H2,1H3;(H2,1,2,3,4)
• InChI key: InChIKey=FDJQHYWUHGBBTO-UHFFFAOYSA-N
• SMILES: COc1ccc(N)cc1N.O=S(=O)(O)O