3-(3-Methyl-3H-diazirine-3-yl)propionic acid

CAS: 25055-86-1

Ref. 3D-FM157144

Product Information

• Name: 3-(3-Methyl-3H-diazirine-3-yl)propionic acid
• Synonyms: 3-Methyl-3H-diazirine-3-propionic acid3-Methyl-diazirine-3-propanoic Acid3-(3-methyl-3H-diazirin-3-yl)propanoic acid
• Brand: Biosynth
• Description: 3-(3-Methyl-3H-diazirine-3-yl)propionic acid (3MDZ) is a fluorophore that can be used in cancer research. It has been shown to bind to the active site of human SIRT1 and inhibit its activity, which leads to cell death by deacylating histone H3. 3MDZ is also able to bind to carbenes, which are highly reactive molecules that have been implicated in aging and cancer. 3MDZ has shown chemopreventive effects against tumor formation and growth by binding to the carbenes and preventing them from forming reactive oxygen species. It can be used as a fluorescent probe for studying the interactions between carbenes and nucleic acids.

Chemical properties

• Molecular weight: 128.13 g/mol
• Formula: C₅H₈N₂O₂
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C5H8N2O2/c1-5(6-7-5)3-2-4(8)9/h2-3H2,1H3,(H,8,9)
• InChI key: InChIKey=DSOGRJSLWCABBW-UHFFFAOYSA-N
• SMILES: CC1(CCC(=O)O)N=N1