5-Methyl L-Glutamate

CAS: 1499-55-4

Ref. 3D-FM15784

Product Information

• Name: 5-Methyl L-Glutamate
• Synonyms: L-Glutamic Acid 5-Methyl EsterH-Glu(OMe)-OH, (2S)-2-Amino-5-methoxy-5-oxo-pentanoic acid, (2S)-2-amino-5-methoxy-5-oxopentanoic acid (non-preferred name), (S)-2-Aminopentanedioic acid 5-methyl ester, (S)-Glutamic acid 5-methyl ester, 2-Amino-5-Methoxy-5-Oxopentanoic Acid (Non-Preferred Name), 4(S)-Carboxy-4-aminobutanoic acid methyl ester, 4-Amino-5-Methoxy-5-Oxopentanoic Acid (Non-Preferred Name), 5-Methyl <span class="text-smallcaps">L</span>-glutamate, 5-Methyl hydrogen <span class="text-smallcaps">L</span>-glutamate, <span class="text-smallcaps">L</span>-Glutamic acid γ-methyl ester, <span class="text-smallcaps">L</span>-Glutamic acid, 5-methyl ester, Glutamic acid 5-methyl ester, Glutamic acid, 5-methyl ester, <span class="text-smallcaps">L</span>-, H-Glu(OMe)-OH, NSC 12959, O-acetyl-L-homoserine, γ-Methyl (S)-glutamate, γ-Methyl <span class="text-smallcaps">L</span>-glutamate, γ-Methyl L-glutamate

Description

5-Methyl L-Glutamate is an antigen that has been shown to be useful in the detection of different types of cancer, including colon, prostate, and breast. The antigens are polymers that can be visualized using a technique called vibrational spectroscopy. Agilent c18 column is used for separation of the polymers. The molecule has been shown to have conformational properties that are dependent on its environment. Lectin binds to the polymer with higher affinity than other molecules and the polymerization initiator is an enzyme that catalyzes the addition of sugar residues to the macromolecule. 5-Methyl L-Glutamate has been shown to inhibit tumor growth in mice with leukemia cells. The inhibitory effect was found to be concentration dependent and had an IC50 value of 0.5 mM which corresponds to a constant (K) of 2 x 10^4 M-1s^-1.

• Brand: Biosynth

Chemical properties

• Molecular weight: 161.16 g/mol
• Formula: C₆H₁₁NO₄
• Purity: Min. 95%