Mangiferin, 98%

CAS: 4773-96-0

Ref. 3D-FM158983

Product Information

• Name: Mangiferin, 98%
• Synonyms: Xanthone-c-glucoside, (1S)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol, (1xi)-1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)-D-glucitol, 1,3,6,7-Tetrahydroxyxanthone-C₂-β-<span class="text-smallcaps">D</span>-glucoside, 1,5-anhydro-1-(1,3,6,7-tetrahydroxy-9-oxo-9H-xanthen-2-yl)hexitol, 2-C-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-1,3,6,7-tetrahydroxyxanthone, 2-β-<span class="text-smallcaps">D</span>-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one, 9H-Xanthen-9-one, 2-β-<span class="text-smallcaps">D</span>-glucopyranosyl-1,3,6,7-tetrahydroxy-, Alpizarin, Alpizarine, Aphloiol, Chinomin, Chinonin, Hedysarid, Mangiferin, NSC 248870, Shamimin, 2-β-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one, 9H-Xanthen-9-one, 2-β-D-glucopyranosyl-1,3,6,7-tetrahydroxy-

Description

Mangiferin is a monosodium salt of mangiferin and has been shown to have DNA-binding activity. It is an activator of the apoptosis pathway and has been shown to inhibit the dinucleotide phosphate (DNP) synthase enzyme, which is involved in nucleotide synthesis. This inhibition prevents cells from making DNA and RNA, leading to cell death. Mangiferin also has hypoglycemic effects in humans due to its ability to inhibit glycolysis. The biological properties of mangiferin are not well understood but it has been shown that it may be detoxified by enzymes such as cytochrome P450 or glutathione S-transferase. Mangiferin also exhibits anti-cancer activities against colorectal adenocarcinoma cells and human breast cancer cells MDA-MB-231. It acts by inhibiting dextran sulfate (DS) uptake, which is an important component for the proliferation of tumor cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 422.34 g/mol
• Formula: C₁₉H₁₈O₁₁
• Purity: Min. 95%
• Color/Form: Powder