1-Methyl-L-tryptophan

CAS: 21339-55-9

Ref. 3D-FM161183

Product Information

• Name: 1-Methyl-L-tryptophan
• Synonyms: (S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid, 1-Methyl-<span class="text-smallcaps">L</span>-tryptophan, 1-Methyltryptophan, <span class="text-smallcaps">L</span>-(-)-1-Methyltryptophan, <span class="text-smallcaps">L</span>-Tryptophan, 1-methyl-, DL-1-Methyltryptophan, L-(-)-1-Methyltryptophan, L-Tryptophan, 1-methyl-, NSC 77678, Tryptophan, 1-methyl-, <span class="text-smallcaps">L</span>-, Tryptophan, 1-methyl-, L-

Description

1-Methyl-L-tryptophan is an activated form of the amino acid tryptophan. It has been shown to have immunomodulatory effects that are mediated by its ability to inhibit IDO1, which is an enzyme that regulates the production of inflammatory cytokines. 1-Methyl-L-tryptophan has been shown to reduce the severity of abdominal surgery in mice and exhibits anticancer activity against a variety of cancer cells. 1-Methyl-L-tryptophan also has antiemetic properties, as it has been shown to block the activation of 5HT3 receptors in the brainstem. This drug also activates polymerase chain reaction (PCR) and inhibits DNA synthesis by binding directly to DNA polymerase.

• Brand: Biosynth

Chemical properties

• Molecular weight: 218.25 g/mol
• Formula: C₁₂H₁₄N₂O₂
• Purity: Min. 95%
• Color/Form: Powder