(R)-Methyglycidate

CAS: 111058-32-3

Ref. 3D-FM16255

Product Information

• Name: (R)-Methyglycidate
• Synonyms: (2R)-Oxirane-2-Carboxylic Acid Methyl Ester, (R)-Glycidic acid methyl ester, (R)-Methyl glycidate, 2-Oxiranecarboxylic acid methyl ester (2R)-, Methyl (2R)-2-oxiranecarboxylate, Methyl (2R)-Glycidate 97% (94% Ee/Glc), Methyl (2R)-Oxirane-2-Carboxylate, Methyl (2R)-glycidate, Methyl (R)-Oxiranecarboxylate, Oxiranecarboxylic acid, methyl ester, (2R)-, Oxiranecarboxylic acid, methyl ester, (R)-, R-Methyl Oxiranecarboxylate

Description

(R)-Methyglycidate is a synthetic compound that has been shown to be effective in inhibiting the activity of cerebral, mediated, and acetonitrile-mediated lipases. The demethylation of (R)-methyglycidate is catalyzed by superacidic conditions present at pH 0.1. The alkylation with trifluoromethanesulfonic acid leads to inhibition of gelatinase and lipase activities. This compound has also been shown to have inhibitory effects on enzymes involved in cerebral inflammation, including glutamate decarboxylase, phospholipases A2, and cyclooxygenases. These inhibitory effects may be due to the inhibition of arachidonic acid release from phospholipids.

• Brand: Biosynth

Chemical properties

• Molecular weight: 102.09 g/mol
• Formula: C₄H₆O₃
• Purity: Min. 95%
• Color/Form: Colorless Clear Liquid
• InChI: InChI=1S/C4H6O3/c1-6-4(5)3-2-7-3/h3H,2H2,1H3/t3-/m1/s1
• InChI key: InChIKey=YKNYRRVISWJDSR-GSVOUGTGSA-N
• SMILES: COC(=O)[C@H]1CO1