2-Methyl-DL-serine

CAS: 5424-29-3

Ref. 3D-FM166762

Product Information

• Name: 2-Methyl-DL-serine
• Synonyms: 2-Amino-3-hydroxy-2-methylpropanoic acid, 2-Amino-3-hydroxy-2-methylpropionic acid, 2-Methyl-<span class="text-smallcaps">DL</span>-serine, 2-Methylserine, 2-methyl-DL-serine, <span class="text-smallcaps">DL</span>-2-Methylserine, <span class="text-smallcaps">DL</span>-Serine, 2-methyl-, <span class="text-smallcaps">DL</span>-α-(Hydroxymethyl)alanine, <span class="text-smallcaps">DL</span>-α-Methylserine, DL-a-Methylserine, NSC 11203, NSC 12135, NSC 163492, Serine, 2-methyl-, Serine, 2-methyl-, <span class="text-smallcaps">DL</span>-, a-Methyl-D,L-serine, α-Methyl-<span class="text-smallcaps">DL</span>-serine, α-Methylserine

Description

2-Methyl-DL-serine is a metabolite of the amino acid serine. It is synthesized by the enzyme serine dehydratase, which converts L-serine to 2-methyl-L-serine. This product has been shown to inhibit microbial metabolism and has been proposed as a drug target for glycopeptide antibiotics. 2-Methyl-DL-serine is an inhibitor of glycosyltransferases that have high affinity for D-alanine, such as enolase, phosphoglycerate kinase, and pyruvate kinase. In addition, this product inhibits some enzymes involved in glycogen metabolism by binding to the lysosomal enzyme α-glucosidase. The enzyme genes that encode for these enzymes are expressed in both prokaryotes and eukaryotes. 2Methyl DL serine also inhibits dioxygenases (e.g., cytochrome P450) that utilize

• Brand: Biosynth

Chemical properties

• Molecular weight: 119.12 g/mol
• Formula: C₄H₉NO₃
• Purity: Min. 95%
• Color/Form: Powder