Marinobufagenin

CAS: 470-42-8

Ref. 3D-FM167440

Product Information

• Name: Marinobufagenin
• Brand: Biosynth
• Description: Marinobufagenin is a bufadienolide compound, which is isolated from the skin and parotid glands of toads, primarily those belonging to the Bufo genus. This compound is characterized by its ability to inhibit Na⁺/K⁺-ATPase, an enzyme crucial for maintaining the electrochemical gradients of sodium and potassium ions across the cell membrane. By inhibiting this enzyme, Marinobufagenin disrupts ion homeostasis, which can lead to increased intracellular calcium concentrations in cardiac muscle cells. This action enhances the force of cardiac contraction, conferring potent cardiotonic effects.

Chemical properties

• Molecular weight: 400.51 g/mol
• Formula: C₂₄H₃₂O₅
• Purity: Min. 95%