Product Information
- 2-({[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)tricyclo[3.3.1.1~3,7~]decane-2-carboxylic acid
- 2-[[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]tricyclo[3.3.1.1<sup>3,7</sup>]decane-2-carboxylic acid
- Reminertant
- Sr-48692
- Tricyclo[3.3.1.1<sup>3,7</sup>]decane-2-carboxylic acid, 2-[[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]amino]-
Meclinertant (MT) is a neurotensin receptor antagonist that blocks the action of this neurotransmitter on its receptors in the brain and spinal cord. MT has been shown to block neurotensin receptor-mediated glutamate release, cytosolic calcium mobilization, and mitochondrial membrane potential changes in cells. The biological properties of MT have been shown to be useful in treating cancer and radiation-induced damage, as well as for reducing symptoms associated with Parkinson's disease. The pharmacological activity of MT may be due to inhibition of MMP-9 activity and locomotor activity.
Chemical properties
Technical inquiry about: 3D-FM176816 Meclinertant
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