(R)-Mesopram

CAS: 189940-24-7

Ref. 3D-FM25115

Product Information

• Name: (R)-Mesopram
• Synonyms: (5R)-5-(4-Methoxy-3-propoxyphenyl)-5-methyl-2-oxazolidinone, 2-Oxazolidinone, 5-(4-methoxy-3-propoxyphenyl)-5-methyl-, (5R)-, 2-Oxazolidinone, 5-(4-methoxy-3-propoxyphenyl)-5-methyl-, (R)-, 5-(4-Methoxy-3-Propoxyphenyl)-5-Methyl-1,3-Oxazolidin-2-One, Daxalipram, Mesopram, Sh 636, Zk 117137

Description

Mesopram is a prodrug of the antidepressant drug duloxetine, which has been shown to be effective in the treatment of inflammatory bowel disease. It is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) that acts by blocking the reabsorption of these neurotransmitters from the synaptic cleft. The anti-inflammatory effects may also be due to its ability to inhibit nuclear factor kappa-light-chain-enhancer (NF-κB), which is a transcription factor that regulates many inflammatory responses. Mesopram has been shown to have an effect on locomotor activity, intracellular calcium levels, axonal growth, and camp levels.

• Brand: Biosynth

Chemical properties

• Molecular weight: 265.31 g/mol
• Formula: C₁₄H₁₉NO₄
• Purity: Min. 95%
• InChI: InChI=1S/C14H19NO4/c1-4-7-18-12-8-10(5-6-11(12)17-3)14(2)9-15-13(16)19-14/h5-6,8H,4,7,9H2,1-3H3,(H,15,16)/t14-/m0/s1
• InChI key: InChIKey=PCCPERGCFKIYIS-AWEZNQCLSA-N
• SMILES: CCCOc1cc([C@]2(C)CNC(=O)O2)ccc1OC