6-Methoxy-2-naphthoic acid

CAS: 2471-70-7

Ref. 3D-FM25227

Product Information

• Name: 6-Methoxy-2-naphthoic acid
• Synonyms: 2-Methoxy-6-naphthalenecarboxylic acid6-Methoxy-2-naphthalenecarboxylic acidNSC 408786, 2-Methoxy-6-naphthalenecarboxylic acid, 2-Naphthalenecarboxylic acid, 6-methoxy-, 2-Naphthoic acid, 6-methoxy-, 6-Methoxy-2-naphthalenecarboxylic acid, 6-Methoxy-2-naphthalenic acid, 6-Methoxy-naphthalene-2-carboxylic acid, 6-Methoxynaphthalen-2-carboxylic acid, 6-Methoxynaphthalene-2-Carboxylate, NSC 408786

Description

6-Methoxy-2-naphthoic acid (MN) is a cavity amide that has been shown to have an inhibitory effect on the growth of cancer cells. MN has been found to be more effective in inhibiting β-amyrin than caffeine, which may be due to its increased lipophilicity. It also has a higher affinity for adriamycin and enhances its anticancer effects. MN has been shown to be beneficial in treating diabetic patients, as it can reduce blood glucose levels by stimulating insulin release. The pharmacokinetic properties of MN are similar to those of other cavity amides, with rapid absorption and distribution throughout the body. This compound is metabolized in the liver by CYP2C8, CYP2C9, CYP3A4 and CYP3A5 enzymes. Molecular docking analysis of MN with β-amyrin showed that there was a strong interaction between them due to their complementary shapes and charge distributions

• Brand: Biosynth

Chemical properties

• Molecular weight: 202.21 g/mol
• Formula: C₁₂H₁₀O₃
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C12H10O3/c1-15-11-5-4-8-6-10(12(13)14)3-2-9(8)7-11/h2-7H,1H3,(H,13,14)
• InChI key: InChIKey=YZBILXXOZFORFE-UHFFFAOYSA-N
• SMILES: COc1ccc2cc(C(=O)O)ccc2c1