8-Methoxycarbonyloctanoic acid

CAS: 2104-19-0

Ref. 3D-FM25289

Product Information

• Name: 8-Methoxycarbonyloctanoic acid
• Synonyms: 8-Carbomethoxyoctanoic acid9-Methoxy-9-oxononanoic acidMethyl hydrogen azelate, 8-Carbomethoxyoctanoic acid, 9-Methoxy-9-Oxononanoic Acid, Ai3-08581, Azelaic acid, methyl ester, Azelaic acid, monomethyl ester, Methyl 8-carboxyoctanoate, Monomethyl azelaate, Monomethyl azelate, Monomethyl nonanedioate, NSC 60226, Nonanedioic acid, 1-methyl ester, Nonanedioic acid, monomethyl ester, Methyl hydrogen azelate

Description

8-Methoxycarbonyloctanoic acid is a fatty acid derivative that has been found to be a potent inhibitor of platelet aggregation. It exhibits anti-platelet activity in human pathogens and in the model system studied. The mechanism of this inhibition is not clearly understood, but it may involve the inhibition of the enzyme ns3 protease or an interaction with the cell membrane. 8-Methoxycarbonyloctanoic acid has also shown antibacterial efficacy against human pathogens such as Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Bacillus cereus. This drug also inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuron

• Brand: Biosynth

Chemical properties

• Molecular weight: 202.25 g/mol
• Formula: C₁₀H₁₈O₄
• Purity: Min. 95%
• Color/Form: White/Off-White Solid
• InChI: InChI=1S/C10H18O4/c1-14-10(13)8-6-4-2-3-5-7-9(11)12/h2-8H2,1H3,(H,11,12)
• InChI key: InChIKey=VVWPSAPZUZXYCM-UHFFFAOYSA-N
• SMILES: COC(=O)CCCCCCCC(=O)O