Methyl 2,5-dihydroxycinnamate

CAS: 63177-57-1

Ref. 3D-FM25380

Product Information

• Name: Methyl 2,5-dihydroxycinnamate
• Synonyms: 3-(2,5-Dihydroxyphenyl)-2-propenoic Acid Methyl Ester, 2,4-Dihydroxymethylcinnamate, 2,5-Dihydroxycinnamic acid methyl ester, Methyl 3-(2,5-dihydroxyphenyl)-2-propenoate, 2-Propenoic acid, 3-(2,5-dihydroxyphenyl)-, methyl ester, methyl (2E)-3-(2,5-dihydroxyphenyl)prop-2-enoate

Description

Methyl 2,5-dihydroxycinnamate is a tyrosine kinase inhibitor that is used in the treatment of squamous cell carcinoma. It has been shown to inhibit the phosphorylation of tyrosine and protein kinase C (PKC) activity in HL-60 cells. This inhibition leads to the inhibition of signal pathways, such as those initiated by epidermal growth factor (EGF), transforming growth factor beta (TGF-β), and platelet-derived growth factor (PDGF). Methyl 2,5-dihydroxycinnamate also inhibits PGE2 levels in hemocytes from ascidian larvae.

• Brand: Biosynth

Chemical properties

• Molecular weight: 194.18 g/mol
• Formula: C₁₀H₁₀O₄
• Purity: Min. 95%
• InChI: InChI=1S/C10H10O4/c1-14-10(13)5-2-7-6-8(11)3-4-9(7)12/h2-6,11-12H,1H3/b5-2+
• InChI key: InChIKey=BQCNSTFWSKOWMA-GORDUTHDSA-N
• SMILES: COC(=O)/C=C/c1cc(O)ccc1O