(E)-3-O-Methyl entacapone

Ref. 3D-FM25489

Product Information

• Name: (E)-3-O-Methyl entacapone
• Synonyms: (2E)-2-Cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)-2-propenamideEntacapone 3-methyl ether
• Brand: Biosynth
• Description: (E)-3-O-Methyl entacapone is a hydroxy group that has been shown to be an impurity in the bulk drug. It was detected by a test solution and its concentration was determined using regression. The presence of nitro, monocarboxylic acid, 5-nitrovanillin, and acetonitrile can also cause impurities in the bulk drug. (E)-3-O-Methyl entacapone is used as a diluent for potential impurities that may be present in the bulk drug. The flow rate of the amide chromatography was increased to 2 mL/min to increase the separation of (E)-3-O-Methyl entacapone from other impurities.

Chemical properties

• Molecular weight: 319.31 g/mol
• Formula: C₁₅H₁₇N₃O₅
• Purity: Min. 95%