Methyl indolyl-3-glyoxylate

CAS: 18372-22-0

Ref. 3D-FM25516

Product Information

• Name: Methyl indolyl-3-glyoxylate
• Synonyms: Methyl (indol-3-yl)oxoacetateα-Oxo-1H-indole-3-acetic acid methyl ester
• Brand: Biosynth
• Description: Methyl indolyl-3-glyoxylate is an active analogue of hepg2, a protein involved in the synthesis of prenylated proteins. It inhibits the prenylation of proteins and halides by binding to ATP, preventing the formation of a covalent bond between ATP and the protein. Methyl indolyl-3-glyoxylate has been shown to induce apoptosis in HeLa cells by inhibiting cell proliferation and DNA synthesis. This compound also causes g1 phase arrest, which may be due to its ability to alkylate DNA. Methyl indolyl-3-glyoxylate has also been shown to be effective against cancer cells in vitro and in vivo, particularly those that are resistant to other chemotherapeutic drugs.

Chemical properties

• Molecular weight: 203.19 g/mol
• Formula: C₁₁H₉NO₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C11H9NO3/c1-15-11(14)10(13)8-6-12-9-5-3-2-4-7(8)9/h2-6,12H,1H3
• InChI key: InChIKey=VFIJGAWYVXDYLK-UHFFFAOYSA-N
• SMILES: COC(=O)C(=O)c1c[nH]c2ccccc12