N-Methyl naltrexone bromide

CAS: 73232-52-7

Ref. 3D-FM25532

Product Information

• Name: N-Methyl naltrexone bromide
• Synonyms: (5a)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium bromideMethylnaltrexoneMethylnaltrexone bromide, (17RS)-17-(Cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-17-methyl-6- oxomorphinanium bromide, (5Alpha)-17-(Cyclopropylmethyl)-3,14-Dihydroxy-17-Methyl-4,5-Epoxymorphinan-17-Ium-6-One Bromide, Methylnaltrexone bromide [USAN], Moa-728, Morphinanium, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-, bromide (1:1), (5α)-, Morphinanium, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-, bromide, (5alpha)-, Mrz 2663, Mrz 2663Br, N-Cyclopropylmethyl-noroxymorphone methobromide, N-Methylnaltrexone bromide, Naltrexone methobromide, Naltrexone methyl bromide, Relistor, Unii-Rfo6Il3D3M, Methylnaltrexone bromide

Description

N-Methyl naltrexone bromide is an opioid antagonist that binds to opioid receptors, preventing the binding of other opioid agonists. It has been shown to be effective in long-term treatment of chronic pain and may be used in combination with opioids for patients with hepatic impairment. The efficacy of N-methyl naltrexone bromide in treating constipation has not been established. This drug should not be used in patients with HIV infection because it may reduce the effectiveness of antiretroviral therapy. The pharmacokinetics and safety profile of this drug have been studied extensively, which showed no serious adverse effects. Histological analysis revealed that N-methyl naltrexone bromide did not affect epithelial mesenchymal cells or the intestinal villi.

• Brand: Biosynth

Chemical properties

• Molecular weight: 436.34 g/mol
• Formula: C₂₁H₂₆BrNO₄
• Purity: Min. 95%