N-Methyl picolinamide
CAS: 6144-78-1
Ref. 3D-FM25544
| 1g | 356.00 € | ||
| 2g | 461.00 € | ||
| 100mg | 78.00 € | ||
| 250mg | 146.00 € | ||
| 500mg | 216.00 € |
Product Information
- N-Methyl-2-pyridinecarboxamideN-Methylpicolinamide
N-Methyl picolinamide is a novel anticancer agent that inhibits the activity of BCR-ABL kinase. It has been shown to be effective against human colon cancer cells (HCT116) and breast cancer cells (MCF-7). N-Methyl picolinamide binds to the ATP binding site of BCR-ABL kinase, inhibiting its enzymatic activity. The compound also binds to annexin II and blocks cell cycle progression at G2/M phase. The chemical structure of N-Methyl picolinamide includes an amide group, which may lead to low bioavailability. This drug has significant inhibitory activities against nitrogen atoms and inhibition constants for both the A and B forms of the enzyme.
Chemical properties
Technical inquiry about: 3D-FM25544 N-Methyl picolinamide
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