Methyl(triphenylphosphoranylidene)acetate

CAS: 2605-67-6

Ref. 3D-FM25581

Product Information

• Name: Methyl(triphenylphosphoranylidene)acetate
• Synonyms: (2-Methoxy-2-Oxoethylidene)Triphenylphosphorane, (Carbomethoxymethylene)triphenylphosphine, (Carbomethoxymethylene)triphenylphosphorane, (Carbomethoxymethylidene)triphenylphosphorane, (Methoxycarbonylmethylene)triphenylphosphorane, (Trifenilfosforanilideno)Acetato De Metilo, (Triphenylphosphoranylidene) methyl acetate, (Triphenylphosphoranylidene)-Aceticacimethylester, (Triphenylphosphoranylidene)Acetic Acid Methyl Ester, (Triphenylphosphoranylidene)acetate de methyle, 2-(Triphenylphosphoranylidene)acetic acid methyl ester, Acetic Acid, (Triphenylphosphoranylidene)-, Methyl Ester, Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester, Aurora Ka-874, Carbethoxymethylene)triphenylphosphorane, Carbmethoxy Methylene Triphenyl Phosphorane, Cmmtpp, Methyl (Triphenyl-Lambda~5~-Phosphanylidene)Acetate, Methyl (triphenylphosphoranyl)acetate, Methyl (triphenylphosphoranylidene)ethanoate, Methyl 2-(triphenyl-λ5-phosphaneylidene)acetate, Methyl 2-(triphenylphosphoranylidene)acetate, Methyl triphenylphosphanylideneacetate, Methyl triphenylphosphonoacetate, Methyl triphenylphosphoranylideneacetate, Methyl triphenylphosphorylideneacetate, Methyl-(triphenylphosphoranyliden)acetat, Nsc 117573, Nsc 407395, Triphenyl(carbomethoxymethylene)phosphorane, [(Methoxycarbonyl)methylene]triphenylphosphorane

Description

Methyl(triphenylphosphoranylidene)acetate is a bicyclic heterocycle with an amino acid sequence that has been determined by x-ray diffraction data. This compound has shown to be an inhibitor of the enzyme glutathione reductase, which converts oxidized glutathione (GSSG) back to the reduced form (GSH). Methyl(triphenylphosphoranylidene)acetate also inhibits other enzymes such as cytochrome p450 and mycobacterium tuberculosis esterases. The reaction mechanism for methyl(triphenylphosphoranylidene)acetate is not yet known but it may involve the formation of an intramolecular hydrogen bond between the NH group and the oxygen atom on C3. This compound has been shown to have anticancer properties in hl-60 cells, which is consistent with its ability to inhibit prostaglandin synthesis. It also has antioxidant properties due

• Brand: Biosynth

Chemical properties

• Molecular weight: 334.35 g/mol
• Formula: C₂₁H₁₉O₂P
• Purity: Min. 98 Area-%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C21H19O2P/c1-23-21(22)17-24(18-11-5-2-6-12-18,19-13-7-3-8-14-19)20-15-9-4-10-16-20/h2-17H,1H3
• InChI key: InChIKey=NTNUDYROPUKXNA-UHFFFAOYSA-N
• SMILES: COC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1