N-Methyl-L-tyrosine - Combretum collinum

CAS: 537-49-5

Ref. 3D-FM25868

Product Information

• Name: N-Methyl-L-tyrosine - Combretum collinum
• Synonyms: Surinamine(+)-N-MethyltyrosineAndirine, (+)-N-Methyltyrosine, (2S)-3-(4-Hydroxyphenyl)-2-(methylamino)propanoic acid, (2S)-3-(4-Hydroxyphenyl)-2-(methylazaniumyl)propanoate, <span class="text-smallcaps">L</span>-(+)-N-Methyltyrosine, <span class="text-smallcaps">L</span>-Tyrosine, N-methyl-, Andirine, Andrine, N-Methyl-<span class="text-smallcaps">L</span>-tyrosine, N-Methyl-L-tyrosine, Ratanhin, Ratanhine, Surinamin, Surinamine, Tyr(AC), Tyrosine, N-methyl-, <span class="text-smallcaps">L</span>-

Description

N-Methyl-L-tyrosine is a molecule that has been studied as a potential treatment for Parkinson's disease. It is chemically related to the amino acid tyrosine and also shares some of its biological properties. N-Methyl-L-tyrosine inhibits the uptake of dopamine by dopamine transporters in cells, which reduces the symptoms of Parkinson's disease. The alkynyl group present in this molecule helps to improve the drug's binding affinity with proctolin, which is a substrate for proton pump inhibitors, and can be used to treat gastrointestinal problems. The clinical use of N-Methyl-L-tyrosine is limited due to its low oral bioavailability; however, it may be effective when administered intravenously or intramuscularly.

• Brand: Biosynth

Chemical properties

• Molecular weight: 195.22 g/mol
• Formula: C₁₀H₁₃NO₃
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C10H13NO3/c1-11-9(10(13)14)6-7-2-4-8(12)5-3-7/h2-5,9,11-12H,6H2,1H3,(H,13,14)/t9-/m0/s1
• InChI key: InChIKey=AXDLCFOOGCNDST-VIFPVBQESA-N
• SMILES: CN[C@@H](Cc1ccc(O)cc1)C(=O)O