Mevastatin

CAS: 73573-88-3

Ref. 3D-FM25991

Product Information

• Name: Mevastatin
• Synonyms: Compactin, 6-demethylvevinolin, CS-500, ML-236 B
• Brand: Biosynth
• Description: Mevastatin is a drug that inhibits the synthesis of cholesterol and has been used to treat hypercholesterolemia. It binds to the hydroxyl group at position 3 on the mevalonate molecule, which prevents the formation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) and consequently reduces the production of cholesterol. Mevastatin has been shown to inhibit mitochondrial functions in wild-type strain yeast cells and myeloma cell lines, which may be due to receptor activity. In addition, it has been shown to induce neuronal death in a polymerase chain reaction assay by inhibiting DNA synthesis.

Chemical properties

• Molecular weight: 390.51 g/mol
• Formula: C₂₃H₃₄O₅
• Purity: Min. 95%
• Color/Form: Powder