(S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid

CAS: 74761-42-5

Ref. 3D-FM32837

Product Information

• Name: (S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid
• Synonyms: (2S)-2-(Methoxycarbonylamino)-3-methylbutanoic acid, (S)-2-((Methoxycarbonyl)Amino)-3-Methylbutanoic Acid, (S)-2-(Methoxycarbonylamino)-3-methylbutanoic acid, (S)-2-Methoxycarbonylamino-3-methylbutyric acid, 2-(S)-[(Methoxycarbonyl)amino]-3-methylbutyric acid, <span class="text-smallcaps">L</span>-Valine, N-(methoxycarbonyl)-, MOC-L-Valine, Moc-Val-OH, N-(Methoxycarbonyl)-<span class="text-smallcaps">L</span>-valine, N-(Methoxycarbonyl)-L-valine, Valine, N-carboxy-, N-methyl ester
• CAS: 74761-42-5

Description

(S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid is a synthetic molecule that has been studied for its antiviral activity against hepatitis C virus. The compound was found to inhibit the replication of the virus, with an IC50 of 0.5 mM in cell culture studies. It also inhibited the replicon and reaction yield of the virus in vitro. (S)-2-((Methoxycarbonyl)amino)-3-methylbutanoic acid is effective against genotype 1 and 2, but not against genotype 3. It is active against a broad range of HCV isolates, including those resistant to other drugs such as ribavirin or telaprevir. The drug has been shown to be well tolerated in animals and humans.
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• Brand: Biosynth

Chemical properties

• Molecular weight: 175.18 g/mol
• Formula: C₇H₁₃NO₄
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C7H13NO4/c1-4(2)5(6(9)10)8-7(11)12-3/h4-5H,1-3H3,(H,8,11)(H,9,10)/t5-/m0/s1
• InChI key: InChIKey=CEFVHPDFGLDQKU-YFKPBYRVSA-N
• SMILES: COC(=O)N[C@H](C(=O)O)C(C)C