Product Information
Name:2-Mercapto-1H-imidazole
Synonyms:
- 2-Mercaptoimidazole
Brand:Biosynth
Description:2-Mercapto-1H-imidazole is an irreversible inhibitor of xanthine oxidase. It binds to the nitrogen atoms of the enzyme's active site and forms a strong hydrogen bond with the oxygen atom of the xanthine substrate. The steric interactions between 2-mercapto-1H-imidazole and the substrate prevent binding and catalysis. The crystal structures of 2-mercapto-1H-imidazole in complex with xanthine oxidase have been determined using X-ray crystallography. FTIR spectroscopy has shown that 2-mercapto-1H-imidazole coordinates in a geometry similar to that of the reactant, hydrochloric acid. Electrochemical impedance spectroscopy (EIS) has revealed that proton transfer takes place when 2-mercapto-1H imidazole binds to xanthine oxidase, which is consistent with reaction mechanism involving elect
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Chemical properties
Molecular weight:100.14 g/mol
Formula:C3H4N2S
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C3H4N2S/c6-3-4-1-2-5-3/h1-2H,(H2,4,5,6)
InChI key:InChIKey=OXFSTTJBVAAALW-UHFFFAOYSA-N
SMILES:S=c1[nH]cc[nH]1
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