4-Methoxybenzoic anhydride

CAS: 794-94-5

Ref. 3D-FM35899

Product Information

• Name: 4-Methoxybenzoic anhydride
• Synonyms: (4-Methoxybenzoyl) 4-methoxybenzoate, 4-Methoxybenzoic acid anhydride, Benzoic acid, 4-methoxy-, 1,1′-anhydride, Benzoic acid, 4-methoxy-, anhydride, NSC 101011, p-Anisic acid anhydride, p-Anisic anhydride, p-Methoxybenzoic anhydride

Description

4-Methoxybenzoic anhydride is a nonsteroidal anti-inflammatory drug (NSAID) that has a hydroxy group, which makes it susceptible to nucleophilic attack. The reaction mechanism of 4-methoxybenzoic anhydride involves hydroxyl group and phosphorus pentachloride. Kinetic data for the reaction was obtained from kinetic studies. The kinetic study found that the rate of the reaction increased with increasing concentration of amines and amides in the reaction mixture. 4-Methoxybenzoic anhydride has been shown to have antiinflammatory activity in various tests on animals, including rats, guinea pigs, and rabbits. The mechanism of this activity may be due to its ability to inhibit prostaglandin synthesis by blocking cyclooxygenase enzyme activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 286.28 g/mol
• Formula: C₁₆H₁₄O₅
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C16H14O5/c1-19-13-7-3-11(4-8-13)15(17)21-16(18)12-5-9-14(20-2)10-6-12/h3-10H,1-2H3
• InChI key: InChIKey=YGMHIBLUWGDWKP-UHFFFAOYSA-N
• SMILES: COc1ccc(C(=O)OC(=O)c2ccc(OC)cc2)cc1