Methazolamide

CAS: 554-57-4

Ref. 3D-FM40873

Product Information

• Name: Methazolamide
• Synonyms: 5-Acetylimino-4-methyl-Δ2-1,3,4-thiadiazoline-2-sulfonamide, 5-Acetylimino-4-methyl-Δ²-1,3,4-thiadiazoline-2-sulfonamide, Acetamide, N-(4-methyl-2-sulfamoyl-Δ2-1,3,4-thiadiazolin-5-ylidene)-, Acetamide, N-(4-methyl-2-sulfamoyl-Δ²-1,3,4-thiadiazolin-5-ylidene)-, L 584601, Metazolamida, Metazolamide, Methazolamid, Methenamide, N-(4-Methyl-2-sulfamoyl-Δ2-1,3,4-thiadiazolin-5-ylidene)acetamide, N-(4-Methyl-2-sulfamoyl-Δ²-1,3,4-thiadiazolin-5-ylidene)acetamide, N-[5-(Aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide, Neptazane, Neptazaneat, 5-Acetylimino-4-methyl-delta(sup 2)-1,3,4-thiadiazoline-2-sulfonamide, Metazolamide [DCIT], Methazolamidum [INN-Latin], Methazolamidum, 4-27-00-08221 (Beilstein Handbook Reference), UNII-W733B0S9SD, Acetamide, N-(5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene)-, Metazolamida [INN-Spanish], BRN 0232387, N-(4-Methyl-2-sulfamoyl-delta(sup 2)-1,3,4-thiadiazolin-5-ylidene)acetamide, N-[(2E)-3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide, Acetamide, N-[5-(aminosulfonyl)-3-methyl-1,3,4-thiadiazol-2(3H)-ylidene]-, 2-Acetylimino-3-methyl-delta(sup 4)-1,3,4-thiadiazoline-5-sulfonamide, HSDB 3269, Methazolamide [INN:BAN:JAN], N-[(2Z)-3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene]acetamide, Acetamide, N-(4-methyl-2-sulfamoyl-delta(sup 2)-1,3,4-thiadiazolin-5-ylidene)-

Description

Methazolamide is a drug that is used to treat eye disorders by reducing the production of aqueous humor, which is the fluid that fills the front part of the eye. Methazolamide inhibits the activity of carbonic anhydrase, which catalyzes the conversion of carbon dioxide and water to bicarbonate and hydrogen ions. This leads to decreased acidity in the fluid inside the eye and prevents edema or swelling. Methazolamide has been shown to inhibit dopamine β-hydroxylase (DBH), an enzyme that converts dopamine into epinephrine. DBH inhibition causes increased levels of dopamine in the body, which can lead to toxicity in some people.

• Brand: Biosynth

Chemical properties

• Molecular weight: 236.27 g/mol
• Formula: C₅H₈N₄O₃S₂
• Purity: Min. 95%