AD-mix-alpha

CAS: 153130-59-7

Ref. 3D-FM46539

Product Information

• Name: AD-mix-alpha
• Brand: Biosynth

Description

AD-mix-alpha is a drug candidate that is being developed to treat hypertension. It is an inhibitor of the enzyme DNA gyrase, which plays an important role in the regulation of bacterial cell division and DNA replication. AD-mix-alpha has been shown to be effective against Pseudomonas aeruginosa and other Gram-negative bacteria. This drug is enantiopure, meaning it contains only one form of the molecule, and therefore does not produce any stereoisomers or diastereomers as byproducts. AD-mix-alpha has been shown to have kinetic and functional properties that are similar to those of glycopeptide antibiotics such as vancomycin. The molecular modeling studies suggest that AD-mix alpha binds to the active site on gyrase through hydrogen bonding interactions with His57, Glu82, Lys87, Asp309, Ser310, and Tyr291. These interactions are similar to those observed for vancomycin. Furthermore,

Chemical properties

• Formula: C₄₈H₅₄N₆O₄•(K₂CO₃)x•(K₂OsO₄•2H₂O)x•(K₃Fe(CN)₆x
• Color/Form: Yellow Powder