5-Methoxy-L-tryptophan

CAS: 25197-96-0

Ref. 3D-FM52239

Product Information

• Name: 5-Methoxy-L-tryptophan
• Synonyms: H-5-MeO-Trp-OHL-2-Amino-3-(5-methoxyindolyl)propionic acid
• Brand: Biosynth
• Description: 5-Methoxy-L-tryptophan is a nonsteroidal anti-inflammatory drug that acts by inhibiting the synthesis of prostaglandins. It has been shown to have a clinical relevance in the treatment of cancer and ischemia reperfusion injury. 5-Methoxy-L-tryptophan has also been shown to be effective in the treatment of inflammatory diseases such as rheumatoid arthritis, ulcerative colitis, and Crohn disease. 5-Methoxy-L-tryptophan is a precursor for serotonin, which regulates many physiological functions including pain perception. Tryptophan has also been found to increase epithelial mesenchymal transition (EMT) and repair mechanisms in fibroblasts. X-ray crystal structures have revealed that 5-methoxy tryptophan binds at the active site of xanthine oxidase, which is an enzyme involved in purine metabolism.

Chemical properties

• Molecular weight: 234.25 g/mol
• Formula: C₁₂H₁₄N₂O₃
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C12H14N2O3/c1-17-8-2-3-11-9(5-8)7(6-14-11)4-10(13)12(15)16/h2-3,5-6,10,14H,4,13H2,1H3,(H,15,16)/t10-/m0/s1
• InChI key: InChIKey=KVNPSKDDJARYKK-JTQLQIEISA-N
• SMILES: COc1ccc2[nH]cc(C[C@H](N)C(=O)O)c2c1