3D-FM52364 - dl-2-methylglutamic-acid-hemihydrate

Applications (2S,4S)-4-Methylglutamic Acid is a potent and selective kainate receptor agonist (1). It has been shown that (2S,4S)-4-Methylglutamic Acid can desensitize kainate receptors and also attenuate capsaicin and inflammatory hyperalgesia (2).
References (1) Donevan, S. D., et al.: J Pharmacol Exp Ther. 285, 539 (1998) (2) Turner, M. S., et al.: Brain Res. 973, 252 (2003)

Stability Hygroscopic
Applications (2S,3R)-3-Methylglutamic Acid Hydrochloride Salt is a derivative of glutamic acid, which is a neurotransmitter that plays crucial physiological roles in the central nervous system (1). (2S,3R)-3-Methylglutamic Acid Hydrochloride Salt inhibits glutamate transport (2). It is also a highly selective and potent agonist for kainate receptors.
References (1) Paola Conti et al., Mini Rev Med Chem 2, 177 (2002) (2) Wehbe, J., et al.: Tetrahedron: Asymmetry 14, 1123 (2003)

Fmoc-a-Me-Glu(OtBu)-OH is a versatile chemical that can be used to synthesize complex compounds in the laboratory. It is a useful building block for organic synthesis and can be used as a reagent, speciality chemical, or useful scaffold. It has been shown to be of high quality and is often used as an intermediate for other compounds. Fmoc-a-Me-Glu(OtBu)-OH is also listed by CAS number 1072845-48-7.

Applications Intermediate in the synthesis of (2S,3R)-3-Methylglutamic Acid, an agonist for kainate receptors.

Applications Protected (S)-Pyroglutaminol (P997525). Intermediate in the synthesis of (2S,3R)-3-Methylglutamic Acid, an agonist for kainate receptors.