4-Morpholinoaniline

CAS: 2524-67-6

Ref. 3D-FM55260

Product Information

• Name: 4-Morpholinoaniline
• Synonyms: (4-(Morpholino)phenyl)amine, 4-(4-Aminophenyl)morpholine, 4-(4-Morpholinyl)-benzenamin, 4-(4-Morpholinyl)aniline, 4-(4-Morpholinyl)benzenamine, 4-(Morpholin-4-Yl)Aniline, 4-(Morpholin-4-yl)phenylamine, 4-Morpholinobenzenamine, 4-N-Morpholinoaniline, Benzenamine, 4-(4-morpholinyl)-, Morpholine, 4-(p-aminophenyl)-, N-(4-aminophenyl)morpholine, NSC 26334, p-Morpholinoaniline

Description

4-Morpholinoaniline is a synthetic substrate that reacts with hydrochloric acid and sodium nitrite to form the reactive intermediate 4-morpholinonitrosobenzene. The reaction mechanism is proposed to proceed through an initial electron transfer from the substrate to the nitrosobenzene intermediate, followed by protonation of the nitrosobenzene nitrogen atom. The resulting 4-nitrophenyl radical abstracts hydrogen from the substrate to give 4-hydroxyphenyl radical. This radical undergoes a nucleophilic attack on the aromatic ring of the substrate molecule, and cleavage of the disulfide bond in the aromatic ring leads to formation of a cyanohydrin product. Studies have been conducted on rat liver microsomes and hepatitis C virus (HCV) to investigate this reaction mechanism.

• Brand: Biosynth

Chemical properties

• Molecular weight: 178.23 g/mol
• Formula: C₁₀H₁₄N₂O
• Purity: Min. 98.5 Area-%
• Color/Form: Red Powder
• InChI: InChI=1S/C10H14N2O/c11-9-1-3-10(4-2-9)12-5-7-13-8-6-12/h1-4H,5-8,11H2
• InChI key: InChIKey=PHNDZBFLOPIMSM-UHFFFAOYSA-N
• SMILES: Nc1ccc(N2CCOCC2)cc1