2-(Methylsulfonyl)aniline

CAS: 2987-49-7

Ref. 3D-FM57994

Product Information

• Name: 2-(Methylsulfonyl)aniline
• Synonyms: (2-Mesylphenyl)amine, 2-(Methanesulfonyl)aniline, 2-(Methylsulfonyl)benzenamine, 2-Aminophenyl methyl sulfone, Aniline, o-(methylsulfonyl)-, Aniline,o-(methylsulfonyl)- (6CI,7CI,8CI), Claasz's sulfurylindoxyl, Claasz'ssulfurylindoxyl, Nsc 55747, o-(Methylsulfonyl)aniline

Description

2-(Methylsulfonyl)aniline is a synthetic chemical that inhibits the activity of the viral NS5B polymerase. It has been shown to have a constant, research-based kinetic for its inhibitory effects on this enzyme. Inhibition occurs through the scission of the N-O bond in 2-(methylsulfonyl)aniline to form 2-aminopurine and methyl sulfate. This reaction also produces a hydroxide solution, which is responsible for the detoxification of 2-(methylsulfonyl)aniline by sodium hydroxide solution. The inhibition of NS5B polymerase leads to an inhibition of RNA synthesis and protein expression. This chemical is not active against bacterial cells, and therefore it can be used as a selective inhibitor for experimental purposes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 171.22 g/mol
• Formula: C₇H₉NO₂S
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C7H9NO2S/c1-11(9,10)7-5-3-2-4-6(7)8/h2-5H,8H2,1H3
• InChI key: InChIKey=AUSRSVRJOXYXMI-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)c1ccccc1N