Fumagillol

CAS: 108102-51-8

Ref. 3D-FM61721

Product Information

• Name: Fumagillol
• Synonyms: 5-Methoxy-4-[2-Methyl-3-(3-Methylbut-2-Enyl)Oxiran-2-Yl]-1-Oxaspiro[2.5]Octan-6-Ol
• Brand: Biosynth
• Description: Fumagillol is a microbial metabolite, which is derived from the fungus *Aspergillus fumigatus*. It exhibits its mode of action primarily through the inhibition of the enzyme methionine aminopeptidase 2 (MetAP2). This inhibition leads to the disruption of angiogenesis, the process by which new blood vessels form, a mechanism that is particularly significant in cancer therapy. Additionally, Fumagillol has demonstrated antimicrobial properties, adding to its potential applications in controlling infections.

Chemical properties

• Molecular weight: 282.38 g/mol
• Formula: C₁₆H₂₆O₄
• Purity: Min. 95%