Fumagillol

CAS: 108102-51-8

Ref. 3D-FM61721

Product Information

• Name: Fumagillol
• Synonyms: 5-Methoxy-4-[2-Methyl-3-(3-Methylbut-2-Enyl)Oxiran-2-Yl]-1-Oxaspiro[2.5]Octan-6-Ol, (3R,4S,5S,6R)-5-Methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]octan-6-ol, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-ol, 1-Oxaspiro(2.5)octan-6-ol, 5-methoxy-4-(2-methyl-3-(3-methyl-2-butenyl)oxiranyl)-, (3R-(3alpha,4alpha(2R*,3R*),5beta,6beta))-, 1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-, (3R,4S,5S,6R)-, 1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-, (3R,4S,5S,6R)-, 1-Oxaspiro[2.5]octan-6-ol, 5-methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-, [3R-[3α,4α(2R*,3R*),5β,6β]]-, 5-methoxy-4-[(2R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-ol, Fos 37, Gelcohol

Description

Fumagillol is a drug that inhibits the growth of cancer cells by binding to and inhibiting the activity of angiogenesis-related protein kinase (AKT). It has been shown to inhibit tumor metastasis in animal models. Fumagillol also inhibits HIV infection and decreases the incidence of AIDS-related cancers in animals. Fumagillol has anti-angiogenic effects, which may be due to its ability to inhibit AKT phosphorylation. Fumagillol is chemically stable and does not show any adverse effects on healthy cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 282.38 g/mol
• Formula: C₁₆H₂₆O₄
• Purity: Min. 95%