(+)-Magnoflorine iodide

CAS: 4277-43-4

Ref. 3D-FM63154

Product Information

• Name: (+)-Magnoflorine iodide
• Synonyms: Thalictrine iodide, 4H-dibenzo[de,g]quinolinium, 5,6,6a,7-tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-, Thalictrine, (S)-5,6,6a,7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium, (6aS)-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium, Magnoflorine, Magnoflorine Iodide, (+)-(Rg)

Description

(+)-Magnoflorine iodide is a compound that inhibits matrix metalloproteinase (MMP) activity. It has been shown to inhibit MMP-2 and MMP-9 at different concentrations, with the IC50 values being 0.5 to 1 μM and 3 to 5 μM, respectively. These results suggest that (+)-Magnoflorine iodide may have therapeutic potential for the treatment of diseases associated with MMPs. The chemical reactions of (+)-Magnoflorine iodide are related to its acidic nature. It undergoes a number of reactions including hydrolysis, oxidation, reduction, and chlorination. Chromatographic analysis has revealed that (+)-Magnoflorine iodide is composed of protopine, cryptopine, dictamnine, and chloride ions. Chelerythrine chloride is a metabolite of this compound which can be detected in urine after oral administration.

• Brand: Biosynth

Chemical properties

• Molecular weight: 469.31 g/mol
• Formula: C₂₀H₂₄NO₄•I
• Purity: Min. 95%
• Color/Form: Powder