(-)-Matairesinol

CAS: 580-72-3

Ref. 3D-FM65434

Product Information

• Name: (-)-Matairesinol
• Synonyms: (3R,4R)-3,4-bis(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one, (3R,4R)-Dihydro-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone, (8R,8′R)-(-)-Matairesinol, 2(3H)-Furanone, dihydro-3,4-bis((4-hydroxy-3-methoxyphenyl)methyl)-, (3R-trans)-, 2(3H)-Furanone, dihydro-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-, 2(3H)-Furanone, dihydro-3,4-divanillyl-, 3R,4R-Bis((4-hydroxy-3-methoxyphenyl)methyl)dihydro-2(3H)-furanone

Description

(-)-Matairesinol is a lignan compound that has been identified as a natural product with antibacterial and antifungal properties. (-)-Matairesinol inhibits the growth of bacteria by binding to the penicillin-binding protein, which prevents the synthesis of bacterial cell walls. It also binds to the 50S ribosomal subunit, inhibiting transcription and translation. (-)-Matairesinol has been shown to have minimal toxicity in vitro, with no significant cytotoxic effects on human HL-60 cells at concentrations up to 500 μM. It also has anti-inflammatory properties, as it can inhibit prostaglandin synthesis. (-)-Matairesinol is currently being investigated as a potential treatment for cancer therapy. 1) 6-Fluoro-3-indoxyl-beta-D-galactopyranoside 2) Tilmicosin 3) 3-Desacetyl

• Brand: Biosynth

Chemical properties

• Molecular weight: 358.39 g/mol
• Formula: C₂₀H₂₂O₆
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C20H22O6/c1-24-18-9-12(3-5-16(18)21)7-14-11-26-20(23)15(14)8-13-4-6-17(22)19(10-13)25-2/h3-6,9-10,14-15,21-22H,7-8,11H2,1-2H3/t14-,15+/m0/s1
• InChI key: InChIKey=MATGKVZWFZHCLI-LSDHHAIUSA-N
• SMILES: COc1cc(C[C@H]2COC(=O)[C@@H]2Cc2ccc(O)c(OC)c2)ccc1O