2-Methylphenoxyacetic acid

CAS: 1878-49-5

Ref. 3D-FM66221

Product Information

• Name: 2-Methylphenoxyacetic acid
• Synonyms: (2-Methylphenoxy)Acetate, (o-Methylphenoxy)acetic acid, (o-Tolyloxy)-acetic acid, 2-(2-Methylphenoxy)acetic acid, 2-(o-Tolyloxy)acetic acid, 2-Methylphenyloxyacetic acid, 2-[(2-Methylphenyl)oxy]acetic acid, Acetic acid, (2-methylphenoxy)-, Acetic acid, (o-tolyloxy)-, Acetic acid, 2-(2-methylphenoxy)-, NSC 5293, o-Cresolglycolic acid, o-Cresoxyacetic acid, o-Cresyloxyacetic acid, o-Tolyloxyacetic acid, (2-Methylphenoxy)acetic acid

Description

2-Methylphenoxyacetic acid is a small-molecule drug that acts as an inhibitor of the protein kinase C (PKC) enzyme. It binds to the active site of PKC and prevents it from phosphorylating other proteins, which ultimately leads to cell death. The PKC enzyme is a potential drug target for cancer and cardiovascular disease because it plays a role in both pathologies. 2-Methylphenoxyacetic acid has been shown to inhibit PKC in vitro and in vivo, with the latter being demonstrated using mathematical modeling and molecular dynamics simulations. 2-Methylphenoxyacetic acid also inhibits annexin II, which is believed to be involved in signal transduction pathways that lead to tumor growth. 2-Methylphenoxyacetic acid has been shown to bind to the hydroxyl group of phospholipids and form hydrogen bonds with amino acids that are important for protein-protein interactions or intermolecular hydrogen bonds.

• Brand: Biosynth

Chemical properties

• Molecular weight: 166.17 g/mol
• Formula: C₉H₁₀O₃
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C9H10O3/c1-7-4-2-3-5-8(7)12-6-9(10)11/h2-5H,6H2,1H3,(H,10,11)
• InChI key: InChIKey=QJVXBRUGKLCUMY-UHFFFAOYSA-N
• SMILES: Cc1ccccc1OCC(=O)O