9-Methyl-2,3,7-trihydroxy-6-fluorone

CAS: 5407-46-5

Ref. 3D-FM69793

Product Information

• Name: 9-Methyl-2,3,7-trihydroxy-6-fluorone
• Synonyms: Methylfluorone, 2,6,7-Trihydroxy-9-Methylxanthen-3-One, 2,6,7-trihydroxy-9-methyl-3H-xanthen-3-one, 3H-Xanthen-3-one, 2,6,7-trihydroxy-9-methyl-, 9-Methyl-2,3,7-trihydroxy-6-fluorone sulphate, NSC 5426, NSC 66209

Description

9-Methyl-2,3,7-trihydroxy-6-fluorone (9MHF) is a natural compound found in honeybee propolis. It has been shown to have anticancer activity against a range of tumour types. 9MHF inhibits the replication of DNA by binding to single-stranded regions in the DNA molecule and preventing the formation of double helices. The optimum concentration for 9MHF is 0.1 μM. At this concentration, it was found that 9MHF had chemoresistance properties and could inhibit replication in staphylococcus cells at concentrations as low as 1 μM. This compound also has antioxidant properties, with redox potentials of -0.09 V and -0.06 V for its oxidized and reduced forms respectively.BR>BR>
9MHF is an inhibitor that binds to basic dyes such as methylene blue or gentian violet and prevents them from binding to the bacterial cell

• Brand: Biosynth

Chemical properties

• Molecular weight: 258.23 g/mol
• Formula: C₁₄H₁₀O₅
• Purity: Min. 95%
• Color/Form: Yellow Powder
• InChI: InChI=1S/C14H10O5/c1-6-7-2-9(15)11(17)4-13(7)19-14-5-12(18)10(16)3-8(6)14/h2-5,15-17H,1H3
• InChI key: InChIKey=TZVNNUHRZXQCHM-UHFFFAOYSA-N
• SMILES: Cc1c2cc(O)c(=O)cc-2oc2cc(O)c(O)cc12