Methyl 4-aminocinnamate

CAS: 65198-02-9

Ref. 3D-FM70773

Product Information

• Name: Methyl 4-aminocinnamate
• Synonyms: 2-Propenoic acid, 3-(4-aminophenyl)-, methyl ester, 3-(4-Aminophenyl)acrylic acid methyl ester, Cinnamic acid, p-amino-, methyl ester, Methyl 3-(4-aminophenyl)-2-propenoate, methyl (2E)-3-(4-aminophenyl)prop-2-enoate, p-Aminocinnamic acid methyl ester

Description

Methyl 4-aminocinnamate is an inhibitor of the integrase enzyme. It inhibits HIV-1 integrase and has been shown to be selective for this enzyme over other cellular enzymes. Methyl 4-aminocinnamate has been shown to inhibit cervical carcinoma, breast carcinoma, and esters as well as inhibiting the growth of human cancer cells in culture. The IC50 for methyl 4-aminocinnamate against cervical carcinoma was found to be in the micromolar range, which is considerably less than that of other anti-cancer agents.

• Brand: Biosynth

Chemical properties

• Molecular weight: 177.2 g/mol
• Formula: C₁₀H₁₁NO₂
• Purity: Min. 95%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C10H11NO2/c1-13-10(12)7-4-8-2-5-9(11)6-3-8/h2-7H,11H2,1H3/b7-4+
• InChI key: InChIKey=HYVLKRMLVXUWQE-QPJJXVBHSA-N
• SMILES: COC(=O)/C=C/c1ccc(N)cc1