Methyl rosmarinate

CAS: 99353-00-1

Ref. 3D-FM74761

Product Information

• Name: Methyl rosmarinate
• Brand: Biosynth
• Description: Methyl rosmarinate is a natural compound that belongs to the class of polymerase chain inhibitors. It is extracted from the acetate extract of Salvia miltiorrhizae. Methyl rosmarinate has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. The extract also has antimicrobial activity against bacteria and fungi, as well as an antagonistic effect on other enzyme inhibitors. Methyl rosmarinate inhibits bacterial growth by binding to DNA-dependent RNA polymerase and prevents transcription and replication. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.

Chemical properties

• Molecular weight: 374.34 g/mol
• Formula: C₁₉H₁₈O₈
• Purity: Min. 97 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C19H18O8/c1-26-19(25)17(10-12-3-6-14(21)16(23)9-12)27-18(24)7-4-11-2-5-13(20)15(22)8-11/h2-9,17,20-23H,10H2,1H3/b7-4+/t17-/m1/s1
• InChI key: InChIKey=XHALVRQBZGZHFE-BBOMDTFKSA-N
• SMILES: COC(=O)[C@@H](Cc1ccc(O)c(O)c1)OC(=O)/C=C/c1ccc(O)c(O)c1