Niclosamide

CAS: 50-65-7

Ref. 3D-FN01544

Product Information

• Name: Niclosamide
• Synonyms: 5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide, 2',5-Dichlor-4'-Nitro-Salizylsaeureanilid, 2',5-Dichloro-4'-Nitrosalicylanilide, 2,5-Dichloro-4-Nitrosalicylanilide, 2-Chloro-4-nitrophenylamide-6-chlorosalicylic acid, 2-Hydroxy-5-Chloro-N-(2-Chloro-4-Nitrophenyl)Benzamide, 5-Chloro-2'-Chloro-4'-Nitrosalicylanilide, 5-Chloro-N-(2-Chloro-4-Nitrophenyl)Salicylamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide, 5-chloro-N-(2-chloro-5-nitrophenyl)-2-hydroxybenzamide, 6-Benzylamino-2(R)-[[1-(hydroxymethyl)-propyl]amino-9-isopropylpurin], Bay 2353, Bayer 2353, Bayer 25648,Bayluscide, Bayer 73, Bayluscid, Benzamide, 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxy-, Cestocid, Cestocide, Devermin, Devermine, Fedal-Telmin, Fenasal, Helmiantin, Hl 2447, Iomesan, Lintex, Mansonil, N-(2-Chloro-4-nitrophenyl)-5-chlorosalicylamide, NSC 178296, Nasemo, Niclocide, Phenasal, Radeverm, Sagimid, Salicylanilide, 2′,5-dichloro-4′-nitro-, Sr 73, Sulqui, Tredemine, Utosamide, Vermitid, Vermitin, Wr 46234, Yomesan, Zestocarp

Description

Chemically a chlorinated salicylanilide, niclosamide is clinically used as an anthelmintic agent. The action of niclosamide has been proven to proceed by inhibiting the STAT3 signaling pathway. Recently, niclosamide, has been considered as an antiproliferative agent in cancer treatment, e.g. melanoma and colorectal cancer. In 2021, niclosamide has been tested for the treatment of COVID-19 patients.

• Brand: Biosynth

Chemical properties

• Molecular weight: 327.12 g/mol
• Formula: C₁₃H₈Cl₂N₂O₄
• Purity: Min. 98 Area-%
• Color/Form: Off-White Powder