Product Information
- 1-(4-Nitrophenyl)Ethanone
- 1-(4-Nitrophenyl)ethan-1-one
- 1-Acetyl-4-nitrobenzene
- 4'-Nitroacetofenona
- 4'-Nitroacetophenon
- 4'-Nitroacetophenone
- 4-Acetyl-1-nitrobenzene
- 4-Acetylnitrobenzene
- 4-Nitrophenyl methyl ketone
- Acetophenone, 4'-nitro-
- See more synonyms
- Acetophenone, p-nitro-
- Ethanone, 1-(4-nitrophenyl)-
- Methyl 4-nitrophenyl ketone
- Methyl p-nitrophenyl ketone
- Nsc 41590
- P-Acetylnitrobenzene
- P-Nitrophenyl Methyl Ketone
4-Nitroacetophenone is an organic compound that has been synthesized in an asymmetric synthesis. It is a nitro compound and a radiosensitizer. The chemical structure of 4-Nitroacetophenone is similar to the structure of phenol, with one nitro group and two hydroxyl groups at opposite ends of the molecule. 4-Nitroacetophenone reacts with radiation to produce free radicals that can damage DNA, RNA, and proteins. The reaction mechanism involves the formation of nitrosating agent (R−NO) which interacts with DNA to form a covalent bond between the DNA base and the nitrosating agent. This covalent bond inhibits DNA replication, leading to cell death. 4-Nitroacetophenone has been shown to be effective in inhibiting cell growth in culture by triggering apoptosis in cells treated with high doses of this drug.
Chemical properties
Technical inquiry about: 3D-FN03712 4-Nitroacetophenone
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