Noscapine base

CAS: 128-62-1

Ref. 3D-FN09246

Product Information

• Name: Noscapine base
• Synonyms: (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo [4, 5-g]isoquinolin-5-yl] phthalide
• Brand: Biosynth
• Description: Noscapine base is a natural alkaloid compound, which is derived from the opium poppy, Papaver somniferum. This bioactive compound modulates the microtubule assembly in cells, impacting the dynamic instability of microtubules, which is crucial in mitosis and cell division. The resultant modulation disrupts microtubule function, thereby exerting a cytostatic effect that hampers the proliferation of malignant cells.

Chemical properties

• Molecular weight: 413.43 g/mol
• Formula: C₂₂H₂₃NO₇
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C22H23NO7/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18/h5-6,9,17-18H,7-8,10H2,1-4H3/t17-,18+/m1/s1
• InChI key: InChIKey=AKNNEGZIBPJZJG-MSOLQXFVSA-N
• SMILES: COc1ccc2c(c1OC)C(=O)O[C@@H]2[C@H]1c2c(cc3c(c2OC)OCO3)CCN1C