Product Information
- 2-[3,5-Bis(trifluoromethyl)phenyl]-N-[6-(4-methylpiperazin-1-yl)-4-o-tolylpyridin-3-yl]-N-methylisobutyramide
- Benzeneacetamide, N,alpha,alpha-trimethyl-N-(4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl)-3,5-bis(trifluoromethyl)-
- Benzeneacetamide, N,α,α-trimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)-
- N,α,α-Trimethyl-N-[4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinyl]-3,5-bis(trifluoromethyl)benzeneacetamide
- Netupitan
- Ro 67-31898/000
Netupitant is an antiemetic drug that is used to treat bowel disease. It has been shown in a two-way crossover study to have biological properties in the treatment of disease activity. Netupitant inhibits the neurokinin-1 receptor and matrix effect, which are responsible for the development of cancerous cells. The drug also has inhibitory properties on p-gp substrates and netupitant, which prevents it from being absorbed by the gastrointestinal tract. This allows netupitant to be transported through the blood-brain barrier into malignant brain tumours, where it can act as a cytotoxic agent.
Chemical properties
Technical inquiry about: 3D-FN103430 Netupitant
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