Nuclear Factor NF-KB Inhibitor SN50 trifluoroacetate salt

CAS: 213546-53-3

Ref. 3D-FN109704

Product Information

• Name: Nuclear Factor NF-KB Inhibitor SN50 trifluoroacetate salt
• Synonyms: H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln- Arg-Lys-Arg-Gln-Lys-Leu-Met-Pro-OH H-AAVALLPAVLLALLAPVQR KRQKLMP-OH
• Brand: Biosynth
• Description: SN50 is a nuclear factor NF-KB inhibitor that blocks the activity of transcription factors that are involved in inflammation and cancer. SN50 inhibits protease activity, which may be due to its ability to bind to response elements on DNA, leading to cytosolic calcium release and activation of signal pathways. It also binds to endothelin-a receptor and induces apoptosis. SN50 has been shown to have anti-tumour effects in resistant breast cancer cells as well as reducing serum aminotransferase levels in rats. This drug also activates transcriptional regulation by binding toll-like receptors and inducing colony stimulating factors. SN50 also has cardioprotective properties, which may be due to its ability to inhibit fatty acid synthase in cardiomyocytes.

Chemical properties

• Molecular weight: 2,781.5 g/mol
• Formula: C₁₂₉H₂₃₀N₃₆O₂₉S
• Purity: Min. 95%