Necrostatin-1 5-(1
CAS: 4311-88-0
Ref. 3D-FN111188
10mg | 353.00 € | ||
25mg | 590.00 € | ||
50mg | 978.00 € | ||
100mg | 1,565.00 € | ||
250mg | 3,401.00 € |
Product Information
- H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone
- MTH-DL-Tryptophan Methylthiohydantoin-DL-tryptophan
- 5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxoimidazolidin-4-one
- Necrostatin-1
- 5-(1H-Indol-3-Ylmethyl)-3-Methyl-2-Thioxo-4-Imidazolidinone
Necrostatin-1 is a small molecule inhibitor that blocks the NF-κB signaling pathway. Necrostatin-1 is a potent inducer of apoptosis and has been shown to inhibit necroptosis in cell culture. It also blocks the Toll-like receptor 4 (TLR4), which is an important death receptor that causes inflammation. Necrostatin-1 has been found to be effective in reducing injury and death in low doses, but has not been tested for long periods of time or at high doses.
Chemical properties
Technical inquiry about: 3D-FN111188 Necrostatin-1 5-(1
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