4-Nitroimidazole
CAS: 3034-38-6
Ref. 3D-FN14780
| 1kg | 514.00 € | ||
| 25g | 136.00 € | ||
| 100g | 192.00 € | ||
| 250g | 272.00 € | ||
| 500g | 416.00 € |
Product Information
- 1H-4-Nitroimidazole
- 1H-5-Nitroimidazole
- 1H-Imidazole, 4-nitro-
- 1H-Imidazole, 5-nitro-
- 4(5)-Nitroimidazole
- 4-Nitro-1H-imidazole
- 5-Nitro-1H-imidazole
- 5-Nitroimidazole
- Imidazole, 4(or 5)-nitro-
- Imidazole, 4-nitro-
- See more synonyms
- NSC 50359
4-Nitroimidazole has a redox potential that is well suited to the reduction of nitro groups. It is an antimicrobial agent that inhibits the growth of microorganisms by inhibiting DNA synthesis. 4-Nitroimidazole can be used for the treatment of infectious diseases such as tuberculosis, leprosy, and brucellosis. In rat liver microsomes, 4-nitroimidazole reacts with NADPH to produce a nitro group and an imidazole ring with a new configuration. The reaction mechanism is based on electron transfer from NADPH to the nitro group in 4-nitroimidazole via a series of reactions that involve cytochrome P450 enzymes. This reaction has kinetic energy and matrix effects that affect its pharmacokinetics and pharmacodynamics.
Chemical properties
Technical inquiry about: 3D-FN14780 4-Nitroimidazole
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