4-Nitroimidazole

CAS: 3034-38-6

Ref. 3D-FN14780

Product Information

• Name: 4-Nitroimidazole
• Synonyms: 1H-4-Nitroimidazole, 1H-5-Nitroimidazole, 1H-Imidazole, 4-nitro-, 1H-Imidazole, 5-nitro-, 4(5)-Nitroimidazole, 4-Nitro-1H-imidazole, 5-Nitro-1H-imidazole, 5-Nitroimidazole, Imidazole, 4(or 5)-nitro-, Imidazole, 4-nitro-, NSC 50359
• CAS: 3034-38-6

Description

4-Nitroimidazole has a redox potential that is well suited to the reduction of nitro groups. It is an antimicrobial agent that inhibits the growth of microorganisms by inhibiting DNA synthesis. 4-Nitroimidazole can be used for the treatment of infectious diseases such as tuberculosis, leprosy, and brucellosis. In rat liver microsomes, 4-nitroimidazole reacts with NADPH to produce a nitro group and an imidazole ring with a new configuration. The reaction mechanism is based on electron transfer from NADPH to the nitro group in 4-nitroimidazole via a series of reactions that involve cytochrome P450 enzymes. This reaction has kinetic energy and matrix effects that affect its pharmacokinetics and pharmacodynamics.

• Brand: Biosynth

Chemical properties

• Molecular weight: 113.07 g/mol
• Formula: C₃H₃N₃O₂
• Purity: Min. 95%
• Color/Form: White Powder