3-Nitroisonicotinaldehyde

CAS: 153813-70-8

Ref. 3D-FN151432

Product Information

• Name: 3-Nitroisonicotinaldehyde
• Brand: Biosynth
• Description: 3-Nitroisonicotinaldehyde is a kinase inhibitor that binds to the ATP binding site of receptor tyrosine kinases. It inhibits the activation of these receptors and prevents the phosphorylation of tyrosine residues on the receptor. 3-Nitroisonicotinaldehyde has been shown to inhibit VEGFR-2, ABCG2, and efflux in human cancer cells. This drug has been shown to inhibit tumor growth in mice by inhibiting angiogenesis, which is a process that involves the formation of new blood vessels from pre-existing ones. 3-Nitroisonicotinaldehyde also inhibits tumor growth by blocking the production of vascular endothelial growth factor (VEGF) from angiogenic cells.

Chemical properties

• Molecular weight: 152.11 g/mol
• Formula: C₆H₄N₂O₃
• Purity: Min. 95%