3-Nitroisonicotinaldehyde
CAS: 153813-70-8
Ref. 3D-FN151432
| 1g | 279.00 € | ||
| 2g | 494.00 € | ||
| 5g | 715.00 € | ||
| 10g | 1,160.00 € | ||
| 500mg | 172.00 € |
Product Information
- 3-Nitro-4-Pyridinecarboxaldehyde
- 3-Nitropyridine-4-Carbaldehyde
- 3-Nitropyridine-4-Carboxaldehyde
- 4-Pyridinecarboxaldehyde, 3-nitro-
3-Nitroisonicotinaldehyde is a kinase inhibitor that binds to the ATP binding site of receptor tyrosine kinases. It inhibits the activation of these receptors and prevents the phosphorylation of tyrosine residues on the receptor. 3-Nitroisonicotinaldehyde has been shown to inhibit VEGFR-2, ABCG2, and efflux in human cancer cells. This drug has been shown to inhibit tumor growth in mice by inhibiting angiogenesis, which is a process that involves the formation of new blood vessels from pre-existing ones. 3-Nitroisonicotinaldehyde also inhibits tumor growth by blocking the production of vascular endothelial growth factor (VEGF) from angiogenic cells.
Chemical properties
Technical inquiry about: 3D-FN151432 3-Nitroisonicotinaldehyde
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